“Autosomal Dominant Polycystic Kidney Disease Epidemiology” report has been added to DelveInsight
Autosomal Dominant Polycystic Kidney Disease Overview
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a genetic disorder which causes pathological cystic changes to the kidney and is characterized by numerous renal and systemic manifestations. Renal manifestations are produced by the progressive and continuous enlargement and proliferation of fluid-filled cysts, leading to enlargement of the kidney up to five times the normal volume in the years prior to the development of kidney failure.
ADPKD may lead to development of end-stage renal disease (ESRD) and is the fourth most common renal disease requiring renal replacement therapy (RRT). The most common extra-renal manifestation is polycystic liver disease (PLD), which is more common in women than in men.
Autosomal Dominant Polycystic Kidney Disease Epidemiology Forecast
Autosomal Dominant Polycystic Kidney Disease epidemiology Historical as well as forecasted epidemiology in the United States, EU5, Japan and China from 2017 to 2030
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Autosomal Dominant Polycystic Kidney Disease Epidemiology Report
Genetic mutation plays a major role in the pathogenesis of ADPKD, mainly mutations in the PKD1, PKD2 genes leads to cyst formation and its progressive growth. ADPKD is often called as “adult PKD” as it mostly presents between 30 and 50 years old.
Key facts of the ADPKD epidemiology report
Autosomal Dominant Polycystic Kidney Disease Epidemiology Segmentation
Autosomal Dominant Polycystic Kidney Disease Treatment
There is no cure for ADPKD and it not possible to stop cysts forming in the kidneys, however, a lot of research has been done in this space to find the ways to manage the disease. Majority of patients with ADPKD will eventually develop ESRD and require RRT. The progressiveness of this disease and its complications cause debilitating effects on health of patients and impose a significant burden, both economically and on the quality of life.
Autosomal Dominant Polycystic Kidney Disease Report Scope
Table of content
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